{"product_id":"taf1-antibody-cat-csb-pa114236","title":"TAF1 Antibody - Cat. #: CSB-PA114236","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:BA2R antibody; CCG1 antibody; CCGS antibody; Cell cycle G1 phase defect antibody; Cell cycle gene 1 protein antibody; Complementation of cell cycle block G1 to S antibody; DYT3 antibody; N TAF1 antibody; NSCL2 antibody; OF antibody; p250 antibody; TAF 1 antibody; TAF(II)250 antibody; TAF1 antibody; TAF1 RNA polymerase II TATA box binding protein (TBP) associated factor 250kDa antibody; TAF1_HUMAN antibody; TAF2A antibody; TAFII-250 antibody; TAFII250 antibody; TATA box binding protein (TBP) associated factor RNA polymerase II A 250kD antibody; TBP associated factor 250 kDa antibody; TBP-associated factor 250 kDa antibody; Transcription factor TFIID p250 polypeptide antibody; Transcription initiation factor TFIID 250 kDa subunit antibody; Transcription initiation factor TFIID subunit 1 antibody; XDP antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P21675\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from internal of Human TAF1.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC; IHC:1:50-1:100\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser\/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Exhibits histone acetyltransferase activity towards histones H3 and H4.\u003cbr\u003e\u003cbr\u003eSekiguchi T., Mol. Cell. Biol. 11:3317-3325(1991).\u003cbr\u003eRuppert S., Nature 362:175-179(1993).\u003cbr\u003eNolte D., Proc. Natl. Acad. Sci. U.S.A. 100:10347-10352(2003).\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:TAF1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483705258084,"sku":"CSB-PA114236","price":867.34,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_598ef946-2480-4733-943c-78f8a9b4c6cc.jpg?v=1660074257","url":"https:\/\/www.genebiosystems.com\/products\/taf1-antibody-cat-csb-pa114236","provider":"GeneBio ","version":"1.0","type":"link"}