Recombinant Rat Vitamin K-dependent protein C(Proc)

Recombinant Rat Vitamin K-dependent protein C(Proc)

CSB-YP018742RA
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Size: 200ug. Other sizes are also available. Please Inquire.

In Stock: No

Lead time: 22-32 working days

Research Topic: Cardiovascular

Uniprot ID: P31394

Gene Names: Proc

Organism: Rattus norvegicus (Rat)

AA Sequence: ANSFLEEVRAGSLERECMEEICDFEEAQEIFQNVEDTLAFWIKYFDGDQCSTPPLDHQCDSPCCGHGTCIDGLGGFSCSCDKGWEGRFCQQEMGFQDCRVKNGGCYHYCLEETRGRRCRCAPGYELADDHMHCRPTVNFPCGKLWKRTDKKRKNFKRDIDPEDEELELGPRIVNGTLTKQGDSPWQAILLDSKKKLACGGVLIHTSWVLTAAHCLESSKKLTVRLGEYDLRRRDPWELDLDIKEVLVHPNYTRSNSDNDIALLRLSQPATLSKTIVPICLPNSGLAQELSQAGQETVVTGWGYQSDKVKDGRRNRTFILTFIRIPLAARNDCMQVMNNVVSENMLCAGIIGDTRDACDGDSGGPMVVFFRGTWFLVGLVSWGEGCGHLNNYGVYTKVGSYLKWIHSYIGERDVSLKSPKL

Expression Region: 42-461aa

Sequence Info: Full Length of Mature Protein

Source: Yeast

Tag Info: N-terminal 6xHis-tagged

MW: 49.3 kDa

Alternative Name(s): Anticoagulant protein C Autoprothrombin IIA Blood coagulation factor XIV

Relevance: Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function.

Reference: "Evaluation of protein C and other biomarkers as predictors of mortality in a rat cecal ligation and puncture model of sepsis." Heuer J.G., Sharma G.R., Gerlitz B., Zhang T., Bailey D.L., Ding C., Berg D.T., Perkins D., Stephens E.J., Holmes K.C., Grubbs R.L., Fynboe K.A., Chen Y.F., Grinnell B., Jakubowski J.A. Crit. Care Med. 32:1570-1578(2004)

Purity: Greater than 85% as determined by SDS-PAGE.

Storage Buffer: Tris-based buffer,50% glycerol

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

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