Recombinant Human Proteasome activator complex subunit 2(PSME2)

Recombinant Human Proteasome activator complex subunit 2(PSME2)

CSB-RP011344h
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Size: 200ug. Other sizes are also available. Please Inquire.

In Stock: No

Lead time: 10-20 working days

Research Topic: Cell Biology

Uniprot ID: Q9UL46

Gene Names: PSME2

Organism: Homo sapiens (Human)

AA Sequence: AKPCGVRLSGEARKQVEVFRQNLFQEAEEFLYRFLPQKIIYLNQLLQEDSLNVADLTSLRAPLDIPIPDPPPKDDEMETDKQEKKEVHKCGFLPGNEKVLSLLALVKPEVWTLKEKCILVITWIQHLIPKIEDGNDFGVAIQEKVLERVNAVKTKVEAFQTTISKYFSERGDAVAKASKETHVMDYRALVHERDEAAYGELRAMVLDLRAFYAELYHIISSNLEKIVNPKGEEKPSMY

Expression Region: 2-239aa

Sequence Info: Full Length

Source: E.coli

Tag Info: N-terminal GST-tagged

MW: 54.3 kDa

Alternative Name(s): 11S regulator complex subunit beta ;REG-betaActivator of multicatalytic protease subunit 2;Proteasome activator 28 subunit beta ;PA28b ;PA28beta

Relevance: Implicated in immunoproteasome assbly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.

Reference: Organization of the genes encoding the human proteasome activators PA28alpha and beta.McCusker D., Wilson M., Trowsdale J.Immunogenetics 49:438-445(1999)

Purity: Greater than 90% as determined by SDS-PAGE.

Storage Buffer: Tris-based buffer,50% glycerol

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

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