Recombinant Human natriuretic peptide B (NPPB),partial

Recombinant Human natriuretic peptide B (NPPB),partial

CSB-EP016021HU(A5)
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Size: 200ug. Other sizes are also available. Please Inquire.

In Stock: Yes

Lead time: 3-7 working days

Research Topic: Signal Transduction

Uniprot ID: P16860

Gene Names: NPPB

Organism: Homo sapiens (Human)

AA Sequence: DLETSGLQEQRNHLQGKLSELQVEQTSLEPLQESP

Expression Region: 37-71aa

Sequence Info: Partial

Source: E.coli

Tag Info: N-terminal GST-tagged

MW: 31 kDa

Alternative Name(s): Gamma-brain natriuretic peptide

Relevance: Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.

Reference: "Human and canine gene homologs of porcine brain natriuretic peptide." Seilhamer J.J., Arfsten A., Miller J.A., Lundquist P., Scarborough R.M., Lewicki J.A., Porter J.G. Biochem. Biophys. Res. Commun. 165:650-658(1989)

Purity: Greater than 90% as determined by SDS-PAGE.

Storage Buffer: Tris-based buffer,50% glycerol

Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.