{"product_id":"phospho-csnk2a1-thr360-ser362-antibody-cat-csb-pa253823","title":"Phospho-CSNK2A1 (Thr360\/Ser362) Antibody - Cat. #: CSB-PA253823","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Casein kinase 2 alpha 1 polypeptide antibody; Casein kinase II alpha 1 antibody; Casein kinase II alpha 1 subunit antibody; Casein kinase II alpha subunit antibody; Casein kinase II subunit alpha antibody; CK II alpha antibody; CK II antibody; CK2 alpha antibody; CK2 catalytic subunit alpha antibody; CK2A1 antibody; CKII antibody; CKIIalpha antibody; CSK21_HUMAN antibody; CSNK2A1 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P68400\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around phosphorylation site of threonine360\/serine 362 (V-P-T(p)-P-S(p)-P-L) derived from Human CK2a.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:1000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The a and a' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53\/TP53 following UV irradiation.\u003cbr\u003e\u003cbr\u003eKeller D.M., Zeng X., et al., Mol. Cell 7:283-292(2001) \u003cbr\u003eKeller D.M., Lu H. et al., J. Biol. Chem. 277:50206-50213(2002)\u003cbr\u003eTrembley J.H., Tatsumi S., et al., Mol. Cell. Biol. 25:1446-1457(2005)\u003cbr\u003eNiefind K., Guerra B., et al., Acta Crystallogr. D 56:1680-1684(2000) \u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Supplied at 1.0mg\/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:CSNK2A1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cell biology;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40484019273828,"sku":"CSB-PA253823","price":1051.32,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_efdbe1db-b0a0-4aef-934f-e9dc8bf813bd.jpg?v=1660086173","url":"https:\/\/www.genebiosystems.com\/products\/phospho-csnk2a1-thr360-ser362-antibody-cat-csb-pa253823","provider":"GeneBio ","version":"1.0","type":"link"}