{"product_id":"pe-cy5-5-anti-mouse-cd49b-pan-nk-cells-antibody-dx5","title":"PE-Cy5.5 Anti-Mouse CD49b\/pan-NK cells Antibody(DX5)","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e: 50T\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget\u003c\/b\u003e: Mouse CD49b\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e: liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugation\u003c\/b\u003e: PE-Cy5.5\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugation Information\u003c\/b\u003e: PE-Cy5.5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 690 nm (e.g., a 690\/50 nm bandpass filter).\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e: 0\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e: 0\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e: Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e: Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone ID\u003c\/b\u003e: DX5\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: IgM, κ\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e: DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b\/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e: 0\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSynonyms\u003c\/b\u003e: CD49 antigen-like family member B|CD49b|Collagen receptor|GPIa|Integrin alpha-2|Platelet membrane glycoprotein Ia|VLA-2 subunit alpha|pan-NK cells\u003c\/p\u003e\u003cp\u003e\u003cb\u003eObserved MW\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniprot ID\u003c\/b\u003e: Q62469\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Application\u003c\/b\u003e: FC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRecommended dilution\u003c\/b\u003e: Volume per test:  5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eimage5\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eGene ID\u003c\/b\u003e: 16398\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Area\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eCatagory\u003c\/b\u003e: Flow cytometry Antibodies\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":47674643218532,"sku":"PC55-30097","price":248.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_bcf09a9b-1e64-4e11-b7c5-61419129d59a.jpg?v=1768001260","url":"https:\/\/www.genebiosystems.com\/products\/pe-cy5-5-anti-mouse-cd49b-pan-nk-cells-antibody-dx5","provider":"GeneBio ","version":"1.0","type":"link"}