{"product_id":"pe-anti-mouse-cd119-antibody-gr-20","title":"PE Anti-Mouse CD119 Antibody(GR-20)","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e: 50T\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget\u003c\/b\u003e: Mouse CD119\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e: liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugation\u003c\/b\u003e: PE\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugation Information\u003c\/b\u003e: PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585\/42 nm bandpass filter).\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e: 0\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e: 0\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e: Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e: Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone ID\u003c\/b\u003e: GR-20\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: IgG2a, κ\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e: CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e: 0\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSynonyms\u003c\/b\u003e: CD119|IFN-gamma-R-alpha|IFN-gamma-R1|Ifngr1|Interferon gamma receptor 1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eObserved MW\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniprot ID\u003c\/b\u003e: P15261\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Application\u003c\/b\u003e: FC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRecommended dilution\u003c\/b\u003e: Volume per test:  5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eimage5\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eGene ID\u003c\/b\u003e: 15979\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Area\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eCatagory\u003c\/b\u003e: Flow cytometry Antibodies\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":47674457129060,"sku":"PE-30207","price":404.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_ba016483-7189-4893-989a-700019596366.jpg?v=1767996740","url":"https:\/\/www.genebiosystems.com\/products\/pe-anti-mouse-cd119-antibody-gr-20","provider":"GeneBio ","version":"1.0","type":"link"}