{"product_id":"mkl1-antibody-cat-csb-pa091375","title":"MKL1 Antibody - Cat. #: CSB-PA091375","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:AI852829 antibody; AMKL antibody; AW743281 antibody; AW821984 antibody; Basic SAP coiled-coil transcription activator antibody; Bsac antibody; KIAA1438 antibody; Mal antibody; Megakaryoblastic leukemia 1 protein antibody; Megakaryocytic acute leukemia protein antibody; MKL (megakaryoblastic leukemia)\/myocardin like 1 antibody; MKL\/myocardin like protein 1 antibody; MKL\/myocardin-like protein 1 antibody; Mkl1 antibody; MKL1_HUMAN antibody; MRTF A antibody; Mrtf A antibody; MRTF-A antibody; MRTFA antibody; MYOCARDIN RELATED PROTEIN antibody; Myocardin related transcription factor A antibody; Myocardin-related transcription factor A antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q969V6\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from N-terminal of Human MKL1.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:3000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation By similarity.\u003cbr\u003e\u003cbr\u003eMa Z., Nat. Genet. 28:220-221(2001).\u003cbr\u003eMercher T., Proc. Natl. Acad. Sci. U.S.A. 98:5776-5779(2001).\u003cbr\u003eNagase T., DNA Res. 7:65-73(2000).\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:MKL1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling;Cancer?Cardiovascular;Metabolism;Signal transduction?Stem cells\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483714400356,"sku":"CSB-PA091375","price":867.34,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_5f57131d-8478-48ff-a03e-578a4009e158.jpg?v=1660074520","url":"https:\/\/www.genebiosystems.com\/products\/mkl1-antibody-cat-csb-pa091375","provider":"GeneBio ","version":"1.0","type":"link"}