{"product_id":"mcl1-antibody-cat-csb-pa274877","title":"MCL1 Antibody - Cat. #: CSB-PA274877","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Bcl 2 related protein EAT\/mcl1 antibody; Bcl-2-like protein 3 antibody; Bcl-2-related protein EAT\/mcl1 antibody; BCL2 related antibody; Bcl2-L-3 antibody; BCL2L3 antibody; EAT antibody; Induced myeloid leukemia cell differentiation protein Mcl 1 antibody; Induced myeloid leukemia cell differentiation protein Mcl-1 antibody; MCL 1 antibody; MCL1 antibody; MCL1-ES antibody; mcl1\/EAT antibody; MCL1_HUMAN antibody; MCL1L antibody; MCL1S antibody; MGC104264 antibody; MGC1839 antibody; Myeloid Cell Leukemia 1 antibody; Myeloid cell leukemia ES antibody; Myeloid cell leukemia sequence 1 antibody; Myeloid cell leukemia sequence 1 BCL2 related antibody; Myeloid cell leukemia sequence 1 isoform 1 antibody; OTTHUMP00000032794 antibody; OTTHUMP00000032795 antibody; TM antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q07820\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around aa.148~152(N-N-T-S-T) derived from Human MCL1.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:1000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.\u003cbr\u003e\u003cbr\u003eBingle C.D., Craig R.W., Swales B.M., Singleton V., Zhou P., Whyte M.K.B.J. Biol. Chem. 275:22136-22146(2000)\u003cbr\u003eZhang D., Li F., Weidner D., Mnjoyan Z.H., Fujise K.J. Biol. Chem. 277:37430-37438(2002)\u003cbr\u003eLeu J.I.-J., Dumont P., Hafey M., Murphy M.E., George D.L.Nat. Cell Biol. 6:443-450(2004)\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Supplied at 1.0mg\/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:MCL1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer;Cell biology;Metabolism\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483692478564,"sku":"CSB-PA274877","price":867.34,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_c1d9a716-df8b-49b2-971d-cdf2daa4fb08.jpg?v=1660074002","url":"https:\/\/www.genebiosystems.com\/products\/mcl1-antibody-cat-csb-pa274877","provider":"GeneBio ","version":"1.0","type":"link"}