{"product_id":"lrp1-antibody-cat-csb-pa249658","title":"LRP1 Antibody - Cat. #: CSB-PA249658","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:A2MR antibody; Alpha 2 macroglobulin receptor antibody; alpha 2MR antibody; Alpha-2-macroglobulin receptor antibody; APOER antibody; Apolipoprotein E receptor antibody; APR antibody; CD 91 antibody; CD91 antibody; CD91 antigen antibody; IGFBP3R antibody; LDL receptor related protein 1 antibody; Low density lipoprotein receptor related protein 1 antibody; Low density lipoprotein related protein 1 antibody; Low-density lipoprotein receptor-related protein 1 intracellular domain antibody; LRP 1 antibody; LRP 515 antibody; LRP 85 antibody; LRP antibody; LRP ICD antibody; LRP-1 antibody; LRP-515 antibody; LRP-85 antibody; Lrp1 antibody; LRP1 protein antibody; LRP1_HUMAN antibody; LRP1A antibody; LRP515 antibody; LRP85 antibody; LRPICD antibody; MGC88725 antibody; Prolow density lipoprotein receptor related protein 1 antibody; TbetaR V\/LRP 1\/IGFBP 3 receptor antibody; TbetaRV\/LRP1\/IGFBP3 receptor antibody; TGFBR 5 antibody; TGFBR5 antibody; Type V tgf beta receptor antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q07954\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthetic peptide of Human LRP1 \u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC; ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen affinity purification\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:LRP1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Neuroscience?Cancer?Cardiovascular?Cell biology;Metabolism;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483476766820,"sku":"CSB-PA249658","price":484.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_7da90770-8109-4c2c-8684-2792b8bc9e01.jpg?v=1660069353","url":"https:\/\/www.genebiosystems.com\/products\/lrp1-antibody-cat-csb-pa249658","provider":"GeneBio ","version":"1.0","type":"link"}