{"product_id":"klf11-antibody-cat-csb-pa594801","title":"KLF11 Antibody - Cat. #: CSB-PA594801","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:9830142A17 antibody; D12Ertd427e antibody; FKLF antibody; FKLF1 antibody; Klf11 antibody; KLF11_HUMAN antibody; Krueppel like factor 11 antibody; Krueppel-like factor 11 antibody; Krueppel-like transcription factor 1 antibody; MODY7 antibody; Tcfcp2l2  antibody; TGFB Early Growth Response 2 antibody; TGFB-inducible early growth response protein 2 antibody; TGFB-inducible early growth response protein 2b antibody; TGFB-inducible early growth response protein 3 antibody; TIEG 2 antibody; TIEG-2 antibody; TIEG-3 antibody; Tieg2b antibody; Transforming Growth Factor Beta Inducible Early Growth Response 2 antibody; Transforming growth factor-beta-inducible early growth response protein 2 antibody; Transforming growth factor-beta-inducible early growth response protein 3 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:O14901\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from Internal of Human KLF11.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:3000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis.\u003cbr\u003e\u003cbr\u003eCook T., J. Biol. Chem. 273:25929-25936(1998).\u003cbr\u003eAsano H., Mol. Cell. Biol. 19:3571-3579(1999).\u003cbr\u003eNeve B., Proc. Natl. Acad. Sci. U.S.A. 102:4807-4812(2005).\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:KLF11\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483699327076,"sku":"CSB-PA594801","price":867.34,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_5596fe60-c2e4-4a54-87eb-416cb554b521.jpg?v=1660074158","url":"https:\/\/www.genebiosystems.com\/products\/klf11-antibody-cat-csb-pa594801","provider":"GeneBio ","version":"1.0","type":"link"}