{"product_id":"kirrel2-antibody-cat-csb-pa946311","title":"KIRREL2 Antibody - Cat. #: CSB-PA946311","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:FILTRIN antibody; Kin of IRRE like 2 (Drosophila) antibody; Kin of IRRE-like protein 2 antibody; Kin of irregular chiasm like 2 antibody; Kin of irregular chiasm-like protein 2 antibody; KIRR2_HUMAN antibody; KIRREL2 antibody; NEPH3 antibody; Nephrin like 3 antibody; nephrin-like gene 1 antibody; Nephrin-like protein 3 antibody; NLG1 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q6UWL6\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Fusion protein of Human KIRREL2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:NEPH3 (nephrin-like protein 3), also referred to as NLG1, FILTRIN or KIRREL2 (kin of IRRE like 2), is a 708 amino acid protein that is a member of the immunoglobulin superfamily of cell adhesion molecules. NEPH3 consists of five extracellular Ig-like repeats, a transmembrane domain, several glycosylation sites and a cytoplasmic domain that has a stretch of nine conserved residues. NEPH3 localizes to the interpodocyte filtration slit in the kidney and to the Langerhans islet beta cells in the pancreas. NEPH3 is thought to be involved in the maintenance of the glomerular filtration barrier in the kidney and in pancreas development. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen affinity purification\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:KIRREL2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cell biology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483257811044,"sku":"CSB-PA946311","price":484.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_698fa6f2-0c6a-4aee-a024-77b8148401c9.jpg?v=1660067382","url":"https:\/\/www.genebiosystems.com\/products\/kirrel2-antibody-cat-csb-pa946311","provider":"GeneBio ","version":"1.0","type":"link"}