{"product_id":"itgb2-antibody-cat-csb-pa066585","title":"ITGB2 Antibody - Cat. #: CSB-PA066585","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:95 subunit beta antibody; Beta 2 (antigen CD18 (p95) antibody; CD 18 antibody; CD18 antibody; Cell surface adhesion glycoprotein LFA 1\/CR3\/P150,959 beta subunit precursor) antibody; Cell surface adhesion glycoproteins LFA 1\/CR3\/p150,95 subunit beta antibody; Cell surface adhesion glycoproteins LFA-1\/CR3\/p150 antibody; Complement component 3 receptor 3 and 4 subunit antibody; Complement receptor C3 beta subunit antibody; Complement receptor C3 subunit beta antibody; Integrin beta 2 antibody; Integrin beta chain beta 2 antibody; Integrin beta-2 (ITGB2) antibody; Integrin beta-2 antibody; Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) antibody; ITB2_HUMAN antibody; ITGB2 antibody; LAD antibody; LCAMB antibody; Leukocyte associated antigens CD18\/11A, CD18\/11B, CD18\/11C antibody; Leukocyte cell adhesion molecule CD18 antibody; LFA 1 antibody; LFA1 antibody; Lymphocyte function associated antigen 1 (LFA1) antibody; Lymphocyte function associated antigen 1 antibody; MAC 1 antibody; MAC1 antibody; Macrophage antigen 1 (mac1) beta antibody; MF17 antibody; MFI7 antibody; OTTHUMP00000115278 antibody; OTTHUMP00000115279 antibody; OTTHUMP00000115280 antibody; OTTHUMP00000115281 antibody; OTTHUMP00000115282 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P05107\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Fusion protein of Human ITGB2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen affinity purification\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:ITGB2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Immunology;Signal transduction?Stem cells\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40482925805668,"sku":"CSB-PA066585","price":484.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_4fc6ffaa-1be2-4efb-93db-58eb4e38b28c.jpg?v=1660059500","url":"https:\/\/www.genebiosystems.com\/products\/itgb2-antibody-cat-csb-pa066585","provider":"GeneBio ","version":"1.0","type":"link"}