{"product_id":"invivomab-anti-mouse-cd274-pd-l1-b7-h1-iv0040","title":"InVivoMAb Anti-Mouse CD274\/PD-L1\/B7-H1 (Iv0040)","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e:100ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDescription\u003c\/b\u003e:Iv0040 is a camelid-derived nanobody fused to a mouse IgG Fc fragment, designed to enhance stability and extend its in vivo half-life. It exhibits a high binding affinity to PD-L1, with a measured dissociation constant (KD) of 0.5 nM. Iv0040 can be effectively used for noninvasive imaging of PD-L1 expression in tumor-bearing mice through SPECT\/CT, enabling real-time monitoring of PD-L1 distribution within the tumor microenvironment.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost species\u003c\/b\u003e:Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies reactivity\u003c\/b\u003e:Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage buffer\u003c\/b\u003e:0.01M PBS, pH 7.4.\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e:\u0026gt;95% as determined by SDS-PAGE.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:VHH-mFc\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications\u003c\/b\u003e:ELISA, Neutralization\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget\u003c\/b\u003e:Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, CD274, Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e:Protein A\/G purified from cell culture supernatant.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eEndotoxin level\u003c\/b\u003e:Please contact us for this information.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAccession\u003c\/b\u003e:Q9EP73\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStability and Storage\u003c\/b\u003e:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone ID\u003c\/b\u003e:Iv0040\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Usage Information\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePredicted molecular weight\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eNote\u003c\/b\u003e:For research use only. Not suitable for clinical or therapeutic use.\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48672584728676,"sku":"MV974010","price":777.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_b8950d15-5bce-460e-b9ba-7bbe6a931639.jpg?v=1782932000","url":"https:\/\/www.genebiosystems.com\/products\/invivomab-anti-mouse-cd274-pd-l1-b7-h1-iv0040","provider":"GeneBio ","version":"1.0","type":"link"}