{"product_id":"invivomab-anti-human-muc16-antibody-ar9-6","title":"InVivoMAb Anti-Human MUC16 Antibody (AR9.6)","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e:100ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDescription\u003c\/b\u003e:AR9.6 is a humanized monoclonal antibody targeting MUC16, with preclinical efficacy against MUC16-associated cancers. It binds strongly to the SEA domain 5 tandem repeat region of MUC16, reduces pancreatic cancer (PDAC) cell migration, and mediates tumor cell killing via ADCC and CDC. In orthotopic PDAC mouse models, AR9.6 significantly decreases tumor growth and proliferation.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost species\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage buffer\u003c\/b\u003e:0.01M PBS, pH 7.4.\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e:\u0026gt;95% as determined by SDS-PAGE.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications\u003c\/b\u003e:ELISA, FCM, Neutralization\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget\u003c\/b\u003e:Mucin-16, CA-125, Ovarian carcinoma antigen CA125, CA125, MUC-16, Ovarian cancer-related tumor marker CA125, MUC16\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e:Protein A\/G purified from cell culture supernatant.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eEndotoxin level\u003c\/b\u003e:Please contact us for this information.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAccession\u003c\/b\u003e:Q8WXI7\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStability and Storage\u003c\/b\u003e:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone ID\u003c\/b\u003e:AR9.6\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Usage Information\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePredicted molecular weight\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eNote\u003c\/b\u003e:For research use only. Not suitable for clinical or therapeutic use.\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48672691388516,"sku":"HV601010","price":777.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_b03449b8-acaf-4598-80cb-1588a3a72096.jpg?v=1782933770","url":"https:\/\/www.genebiosystems.com\/products\/invivomab-anti-human-muc16-antibody-ar9-6","provider":"GeneBio ","version":"1.0","type":"link"}