{"product_id":"il31ra-antibody-cat-csb-pa854162esr1hu","title":"IL31RA Antibody - Cat. #: CSB-PA854162ESR1HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Class I cytokine receptor antibody; CRL 3 antibody; CRL antibody; CRL3 antibody; Cytokine receptor like 3 antibody; Cytokine receptor-like 3 antibody; GLM R antibody; GLM-R antibody; GLMR antibody; Gp130 like monocyte receptor antibody; GP130 like receptor antibody; Gp130-like monocyte receptor antibody; Gp130-like receptor antibody; GPL antibody; HGLM R antibody; HGLM-R antibody; HGLMR antibody; IL 31 receptor subunit alpha antibody; IL 31R subunit alpha antibody; IL 31RA antibody; IL-31 receptor subunit alpha antibody; IL-31R subunit alpha antibody; IL-31R-alpha antibody; IL-31RA antibody; IL31 receptor subunit alpha antibody; IL31R subunit alpha antibody; IL31R_HUMAN antibody; IL31RA antibody; Interleukin 31 receptor A antibody; interleukin 31 receptor subunit alpha antibody; Interleukin-31 receptor subunit alpha antibody; MGC125346 antibody; PLCA 2 antibody; PLCA2 antibody; PRO21384 antibody; Soluble type I cytokine receptor CRL3 antibody; ZcytoR17 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q8NI17\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Interleukin-31 receptor subunit alpha protein (1-300AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC; Recommended dilution: IHC:1:20-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 (PubMed:11877449, PubMed:14504285, PubMed:15627637, PubMed:15194700). May function in skin immunity (PubMed:15184896). Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (By similarity). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (By similarity).\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen Affinity Purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:IL31RA\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling; Immunology; Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40486127763556,"sku":"CSB-PA854162ESR1HU","price":484.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_c76aae58-e570-4ae3-9886-dae1fb19d16c.jpg?v=1660141141","url":"https:\/\/www.genebiosystems.com\/products\/il31ra-antibody-cat-csb-pa854162esr1hu","provider":"GeneBio ","version":"1.0","type":"link"}