{"product_id":"human-liver-carboxylesterase-1-ces1-elisa-kit","title":"Human Liver Carboxylesterase 1, CES1 ELISA Kit","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e:96 Tests-1 Kit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (PubMed: 7980644, PubMed: 9169443, PubMed: 9490062, PubMed: 18762277). Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester (PubMed: 7980644, PubMed: 9169443, PubMed: 9490062, PubMed: 18762277). Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine (PubMed: 7980644). Catalyzes the transesterification of cocaine to form cocaethylene (PubMed: 7980644). Displays fatty acid ethyl ester Synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate (PubMed: 7980644). Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins (PubMed: 21049984). Hydrolyzes cellular cholesteryl esters to free cholesterols and promotes reverse cholesterol transport (RCT) by facilitating both the initial and final steps in the process (PubMed: 18762277, PubMed: 16024911, PubMed: 11015575, PubMed: 16971496). First of all, allows free cholesterol efflux from macrophages to extracellular cholesterol acceptors and secondly, releases free cholesterol from lipoprotein-delivered cholesteryl esters in the liver for bile acid synthesis or direct secretion into the bile (PubMed: 18762277, PubMed: 18599737, PubMed: 16971496).\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch_area\u003c\/b\u003e:Cardiovascular\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications\u003c\/b\u003e:ELISA\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget_protein\u003c\/b\u003e:CES1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAssay type\u003c\/b\u003e:Sandwich\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSensitivity\u003c\/b\u003e:0.46ng\/ml\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDetection range\u003c\/b\u003e:1-40ng\/ml\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSample type\u003c\/b\u003e:Serum, plasma or other biological fluids\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFull product name\u003c\/b\u003e:Liver Carboxylesterase 1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e:2-8ºC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAssay time\u003c\/b\u003e:1h 30m\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt accession\u003c\/b\u003e:P23141\u003c\/p\u003e\u003cp\u003e\u003cb\u003eMASS(Da)\u003c\/b\u003e:62,521\u003c\/p\u003e\u003cp\u003e\u003cb\u003eGeneID\u003c\/b\u003e:1066\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSynonyms\u003c\/b\u003e:ACAT;Acyl-coenzyme A:cholesterol acyltransferase;Brain carboxylesterase hBr1;Carboxylesterase 1;CE-1;CEH;CES 1;CES1;Cholesteryl ester hydrolase;Cocaine carboxylesterase;Egasyn;hCE-1;HMSE;Liver carboxylesterase 1;Methylumbelliferyl-acetate deacetylase 1;Monocyte\/macrophage serine esterase;REH;Retinyl ester hydrolase;Serine esterase 1;TGH;Triacylglycerol hydrolase\u003c\/p\u003e\u003cp\u003e\u003cb\u003eGene names\u003c\/b\u003e:CES1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStandard solution\u003c\/b\u003e:48ng\/ml\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":40500639989860,"sku":"E2395Hu","price":1025.92,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_e2bb1ae6-0a9a-407e-ac58-9f9575cf9b3a.jpg?v=1660528181","url":"https:\/\/www.genebiosystems.com\/products\/human-liver-carboxylesterase-1-ces1-elisa-kit","provider":"GeneBio ","version":"1.0","type":"link"}