{"product_id":"hey1-antibody-fitc-conjugated-cat-csb-pa896909lc01hu","title":"HEY1 Antibody, FITC conjugated - Cat. #: CSB-PA896909LC01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Basic helix loop helix protein OAF1 antibody; bHLHb31 antibody; Cardiovascular helix loop-helix factor 2 antibody; Cardiovascular helix-loop-helix factor 2 antibody; CHF-2 antibody; CHF2 antibody; Class B basic helix-loop-helix protein 31 antibody; Hairy and enhancer of split related protein 1 antibody; Hairy and enhancer of split-related protein 1 antibody; Hairy enhancer-of-split related with YRPW motif protein 1 antibody; Hairy related transcription factor 1 antibody; Hairy-related transcription factor 1 antibody; Hairy\/enhancer of split related with YRPW motif 1 antibody; Hairy\/enhancer-of-split related with YRPW motif protein 1 antibody; HERP2 antibody; HES related repressor protein 1 antibody; HES-related repressor protein 1 antibody; HES-related repressor protein 2 antibody; HESR-1 antibody; HESR1 antibody; HEY 1 antibody; hey1 antibody; HEY1_HUMAN antibody; hHRT1 antibody; HRT-1 antibody; HRT1 antibody; OAF1 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q9Y5J3\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Hairy\/enhancer-of-split related with YRPW motif protein 1 protein (200-300AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Transcriptional repressor which binds preferentially to the canonical E box sequence 5\\'-CACGTG-3\\' (PubMed:11095750). Downstream effector of Notch signaling required for cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY2 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1\/MASH1 and NEUROD4\/MATH3 (PubMed:15485867). Involved in the regulation of liver cancer cells self-renewal (PubMed:25985737).\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:FITC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, pH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:HEY1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling; Cardiovascular\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40487312982116,"sku":"CSB-PA896909LC01HU","price":484.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_567a4af1-5ed3-4d12-a1d2-364ce45f4e82.jpg?v=1660163088","url":"https:\/\/www.genebiosystems.com\/products\/hey1-antibody-fitc-conjugated-cat-csb-pa896909lc01hu","provider":"GeneBio ","version":"1.0","type":"link"}