{"product_id":"finetest-r-700-anti-mouse-cd115-csf-1r-antibody-afs98","title":"FineTest®700 Anti-Mouse CD115\/CSF-1R Antibody(AFS98)","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e: 50T\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget\u003c\/b\u003e: Mouse CD115\/CSF\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e: liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugation\u003c\/b\u003e: FineTest®700\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugation Information\u003c\/b\u003e: FineTest® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725\/40 nm bandpass filter).\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e: 0\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e: 0\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e: Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e: Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone ID\u003c\/b\u003e: AFS98\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: IgG2a, κ\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e: CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes\/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e: 0\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSynonyms\u003c\/b\u003e: CD115|CSF-1 receptor (EC: 2.7.10.1)|CSF-1-R|CSF-1R|Csf1r|Csfmr|Fms|M-CSF-R|Macrophage colony-stimulating factor 1 receptor|Proto-oncogene c-Fms\u003c\/p\u003e\u003cp\u003e\u003cb\u003eObserved MW\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniprot ID\u003c\/b\u003e: P09581\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Application\u003c\/b\u003e: FC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRecommended dilution\u003c\/b\u003e: Volume per test:  5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eimage5\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eGene ID\u003c\/b\u003e: 12978\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Area\u003c\/b\u003e: \u003c\/p\u003e\u003cp\u003e\u003cb\u003eCatagory\u003c\/b\u003e: Flow cytometry Antibodies\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":47674412138596,"sku":"F700-30157","price":323.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_700ec13a-f383-47af-b78c-52f11c738e3c.jpg?v=1767995702","url":"https:\/\/www.genebiosystems.com\/products\/finetest-r-700-anti-mouse-cd115-csf-1r-antibody-afs98","provider":"GeneBio ","version":"1.0","type":"link"}