{"product_id":"finetest-r-594-anti-human-vegfr2-cd309-antibody","title":"FineTest®594 Anti-Human VEGFR2\/CD309 Antibody","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e: 25T\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget\u003c\/b\u003e: Human VEGFR2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e: liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugation\u003c\/b\u003e: FineTest®594\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugation Information\u003c\/b\u003e: FineTest®594 is optimally excited by the green-yellow laser (561–594 nm) and detected using an optical filter centered near 615 nm (e.g., a 615\/20 nm bandpass filter).\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e: 0\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e: 0\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e: Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e: monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone ID\u003c\/b\u003e: 3K4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e: KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand\/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e: Vascular endothelial growth factor receptor 2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSynonyms\u003c\/b\u003e: Vascular endothelial growth factor receptor 2 (VEGFR-2)|Fetal liver kinase 1 (FLK-1)|Kinase insert domain receptor (KDR)|Protein-tyrosine kinase receptor flk-1|KDR|FLK1|VEGFR2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eObserved MW\u003c\/b\u003e: 0\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniprot ID\u003c\/b\u003e: P35968\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Application\u003c\/b\u003e: FC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRecommended dilution\u003c\/b\u003e: Volume per test:  5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eimage5\u003c\/b\u003e: 0\u003c\/p\u003e\u003cp\u003e\u003cb\u003eGene ID\u003c\/b\u003e: 3791\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Area\u003c\/b\u003e: 0\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCatagory\u003c\/b\u003e: Flow cytometry Antibodies\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":47660455723108,"sku":"F594-30163","price":476.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_88be5546-3891-4342-bb39-697574dd3d85.jpg?v=1767905810","url":"https:\/\/www.genebiosystems.com\/products\/finetest-r-594-anti-human-vegfr2-cd309-antibody","provider":"GeneBio ","version":"1.0","type":"link"}