{"product_id":"faslg-antibody-cat-csb-pa243242","title":"FASLG Antibody - Cat. #: CSB-PA243242","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:ALPS1B antibody; Apoptosis (APO 1) antigen ligand 1 antibody; Apoptosis antigen ligand 1 antibody; Apoptosis antigen ligand antibody; APT1LG1 antibody; APTL antibody; CD178 antibody; CD178 antigen antibody; CD95 ligand antibody; CD95-L antibody; CD95L antibody; CD95L protein antibody; Fas antigen ligand antibody; Fas L antibody; Fas ligand (TNF superfamily member 6) antibody; Fas ligand antibody; FASL antibody; Fasl Fas ligand (TNF superfamily member 6) antibody; FASLG antibody; Generalized lymphoproliferative disease antibody; Gld antibody; soluble form antibody; TNFL6_HUMAN antibody; TNFSF6 antibody; Tumor necrosis factor (ligand) superfamily member 6 antibody; Tumor necrosis factor ligand superfamily member 6 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P48023\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from internal of Human FAS ligand.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Cytokine that binds to TNFRSF6\/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6\/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B\/DcR3 modulates its effects. The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition.\u003cbr\u003e\u003cbr\u003eAlderson M.; J. Exp. Med. 181:71-77(1995).\u003cbr\u003eTakahashi T., Int. Immunol. 6:1567-1574(1994).\u003cbr\u003eGregory S.G., ure 441:315-321(2006).\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:FASLG\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cell biology;Immunology;Stem cells\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483999514724,"sku":"CSB-PA243242","price":867.34,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_833075ab-397c-4b4f-b332-1c17b2d7c5b7.jpg?v=1660085789","url":"https:\/\/www.genebiosystems.com\/products\/faslg-antibody-cat-csb-pa243242","provider":"GeneBio ","version":"1.0","type":"link"}