Bovine pancreatic deoxyribonuclease (DNase I) is an endonuclease which splits phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide yielding polynucleotides with free hydroxyl group at the 3' position and phosphate group at the 5' position. Activity ≥ 2000 Kunitz units/mg powder. Higher purity for most demanding applications.
The optimum pH is 7.8. DNase I is activated by bivalent metals, and inhibited by chelating agents such EDTA and sodium dodecyl sulfate. DNase I can be stabilized against proteolytic digestion by 5 mM Ca2+.
The Deoxyribonuclease (DNase I) has been chromatographically purified to remove trace contaminating proteases. DNase may be used in clinic to thin and liquefy mucus in the lungs. RNase free.
Higherquality DNase I
Higher purity DNase I offer OEM and bulk package.
Higher quality Deoxyribonuclease
Source: Bovine Pancrease
SPECIFICATION: High Specific Activity ≥ 2000 Kunitz units/mg powder