{"product_id":"cyp3a4-antibody-cat-csb-pa178836","title":"CYP3A4 Antibody - Cat. #: CSB-PA178836","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:1,8-cineole 2-exo-monooxygenase antibody; Albendazole monooxygenase antibody; Albendazole sulfoxidase antibody; CP33 antibody; CP34 antibody; CP3A4_HUMAN antibody; CYP3 antibody; CYP3A antibody; CYP3A3 antibody; CYP3A4 antibody; CYPIIIA3 antibody; CYPIIIA4 antibody; Cytochrome P450 3A3 antibody; Cytochrome P450 3A4 antibody; Cytochrome P450 family 3 subfamily A polypeptide 4 antibody; Cytochrome P450 HLp antibody; Cytochrome P450 NF-25 antibody; Cytochrome P450 subfamily IIIA polypeptide 4 antibody; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 antibody; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antibody; Cytochrome P450-PCN1 antibody; Glucocorticoid inducible P450 antibody; HLP antibody; MGC126680 antibody; NF 25 antibody; NF25 antibody; Nifedipine oxidase antibody; P450 III steroid inducible antibody; P450 PCN1 antibody; P450, family III antibody; P450C3 antibody; P450PCN1 antibody; Quinine 3 monooxygenase antibody; Quinine 3-monooxygenase antibody; Taurochenodeoxycholate 6 alpha hydroxylase antibody; Taurochenodeoxycholate 6-alpha-hydroxylase antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P08684\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Fusion protein of Human CYP3A4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. \u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen affinity purification\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:CYP3A4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer?Cardiovascular;Metabolism;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40482774810724,"sku":"CSB-PA178836","price":484.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_90819040-5331-4ce7-8589-0b956cec68fa.jpg?v=1660056246","url":"https:\/\/www.genebiosystems.com\/products\/cyp3a4-antibody-cat-csb-pa178836","provider":"GeneBio ","version":"1.0","type":"link"}