{"product_id":"cyp27a1-antibody-cat-csb-pa446866","title":"CYP27A1 Antibody - Cat. #: CSB-PA446866","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:12-alpha-triol 27-hydroxylase antibody; 5-beta-cholestane-3-alpha antibody; 5-beta-cholestane-3-alpha; 7-alpha; 12-alpha-triol 26-hydroxylase antibody; 5-beta-cholestane-3-alpha; 7-alpha; 12-alpha-triol 27-hydroxylase antibody; 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase antibody; 7-alpha antibody; Cholestanetriol 26 monooxygenase antibody; CP27 antibody; CP27A_HUMAN antibody; CTX antibody; CYP antibody; CYP27 antibody; CYP27A1 antibody; Cytochrome P 450C27\/25 antibody; Cytochrome P-450C27\/25 antibody; Cytochrome P450 27 antibody; Cytochrome P450 27 mitochondrial antibody; Cytochrome P450 family 27 subfamily A member 1 antibody; Cytochrome P450 family 27 subfamily A polypeptide 1 antibody; Cytochrome P450 subfamily XXVIIA (steroid 27-hydroxylase cerebrotendinous xanthomatosis) polypeptide 1 antibody; mitochondrial antibody; Sterol 26 hydroxylase antibody; Sterol 26 hydroxylase mitochondrial antibody; Sterol 26-hydroxylase antibody; Sterol 27 hydroxylase antibody; Sterol 27-hydroxylase antibody; Vitamin D(3) 25 hydroxylase antibody; Vitamin D(3) 25-hydroxylase antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q02318\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Fusion protein of Human CYP27A1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen affinity purification\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:CYP27A1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer?Cardiovascular;Metabolism;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40482891038820,"sku":"CSB-PA446866","price":484.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_6321bb09-7332-4d4b-9ee3-c0049d0500ee.jpg?v=1660058905","url":"https:\/\/www.genebiosystems.com\/products\/cyp27a1-antibody-cat-csb-pa446866","provider":"GeneBio ","version":"1.0","type":"link"}