{"product_id":"cd3-epsilon-antibody-cat-fnab01458","title":"CD3 epsilon antibody , Cat. #  FNab01458","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e:100ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e:Immunogen affinity purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e:?95% as determined by SDS-PAGE\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone ID\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha\/beta and gamma\/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:CD3e molecule, epsilon (CD3-TCR complex)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSynonyms\u003c\/b\u003e:CD3, CD3 epsilon, CD3E, CD3-epsilon, T3E, TCRE\u003c\/p\u003e\u003cp\u003e\u003cb\u003eObserved MW\u003c\/b\u003e:23 kDa\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniprot ID\u003c\/b\u003e:P07766\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Application\u003c\/b\u003e:ELISA, WB, IHC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRecommended dilution\u003c\/b\u003e:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eGene ID\u003c\/b\u003e:916\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Area\u003c\/b\u003e:Cancer, Immunology, Signal Transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40499413221476,"sku":"FNab01458","price":527.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_520b3293-26ea-4cc1-a7b7-77ccceee71a3.jpg?v=1660499879","url":"https:\/\/www.genebiosystems.com\/products\/cd3-epsilon-antibody-cat-fnab01458","provider":"GeneBio ","version":"1.0","type":"link"}