{"product_id":"anti-hrsv-fusion-protein-reference-antibody-motavizumab-ruo","title":"Anti-HRSV Fusion Protein Reference Antibody (Motavizumab, RUO)","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e:100ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDescription\u003c\/b\u003e:Motavizumab (MEDI-524, NUMAX, NISTmAb) is a second generation monoclonal antibody (mAb) derived from palivizumab (Synagis) using affinity maturation techniques. Motavizumab is currently undergoing US Food and Drug Administration review as a treatment for respiratory syncytial virus (RSV) prophylaxis. It has been evaluated in large-scale clinical studies, and has demonstrated efficacy in reducing the disease burden of RSV in high-risk infant populations. Motavizumab (MEDI-524, NUMAX, NISTmAb) has higher affinity and a longer half-life, was effective in reducing RSV hospitalization in high-risk full-term infants in the US, but was not licensed due to safety concerns (allergic reactions).\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost species\u003c\/b\u003e:Humanized\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested applications\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies reactivity\u003c\/b\u003e:HRSV-A\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage buffer\u003c\/b\u003e:0.01M PBS, pH 7.4.\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e:\u0026gt;95% purity as determined by SDS-PAGE.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG1, kappa\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications\u003c\/b\u003e:ELISA, Bioactivity: FACS, Functional assay, Research in vivo\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget\u003c\/b\u003e:F, Fusion glycoprotein F0, Fusion glycoprotein F2, p27, Intervening segment, Pep27, Peptide 27, Fusion glycoprotein F1\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e:Protein A\/G purified from cell culture supernatant.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eEndotoxin level\u003c\/b\u003e:Please contact us for this information.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eExpression system\u003c\/b\u003e:Mammalian Cells\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAccession\u003c\/b\u003e:P03420\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStability and Storage\u003c\/b\u003e:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReconstitution\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAlternative Names\u003c\/b\u003e:MEDI-524, NUMAX, NISTmAb, CR9503, 677010-34-3\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone ID\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eNote\u003c\/b\u003e:For research use only. Not suitable for clinical or therapeutic use.\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48672950714468,"sku":"VK421036","price":369.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_31d0e92f-94a6-4285-8081-74af5e9c0108.jpg?v=1782939752","url":"https:\/\/www.genebiosystems.com\/products\/anti-hrsv-fusion-protein-reference-antibody-motavizumab-ruo","provider":"GeneBio ","version":"1.0","type":"link"}