{"product_id":"anapc1-antibody-cat-csb-pa549756","title":"ANAPC1 Antibody - Cat. #: CSB-PA549756","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:ANAPC 1 antibody; Anapc1 antibody; Anaphase promoting complex subunit 1 antibody; anaphase-promoting complex 1 (meiotic checkpoint regulator) antibody; Anaphase-promoting complex subunit 1 antibody; Apc 1 antibody; APC1 antibody; APC1_HUMAN antibody; Cyclosome subunit 1 antibody; MCPR antibody; Meiotic checkpoint regulator antibody; Mitotic checkpoint regulator antibody; Protein Tsg 24 antibody; Protein Tsg24 antibody; Testis-specific gene 24 protein antibody; TSG 24 antibody; TSG24 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q9H1A4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from internal of Human Cyclosome 1.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IF; IF:1:100-1:500\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Component of the anaphase promoting complex\/cyclosome (APC\/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC\/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.\u003cbr\u003e\u003cbr\u003eJoergensen P.M., Gene 262:51-59(2001).\u003cbr\u003eOta T., Nat. Genet. 36:40-45(2004).\u003cbr\u003eKraft C., EMBO J. 22:6598-6609(2003).\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:ANAPC1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cell biology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483723116644,"sku":"CSB-PA549756","price":867.34,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_d9e71886-742a-4d2b-adf0-f6f68a717892.jpg?v=1660074727","url":"https:\/\/www.genebiosystems.com\/products\/anapc1-antibody-cat-csb-pa549756","provider":"GeneBio ","version":"1.0","type":"link"}