Ideal for the separation of small DNA fragments (e.g., PCR products) differing in size by as little as 2% and compares to the resolution of DNA in polyacrylamide gels. High resolution agarose is also ideal for resolving amplification fragment length polymorphisms (AmpFLP), short tandem repeats (STR) and tri- and tetranucleotide repeats. Lower ethidium bromide and SYBR Green background staining.
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You can have resolution of DNA and RNA similar to that seen with polyacrylamide gels.