{"product_id":"uba2-antibody-cat-csb-pa096056","title":"UBA2 Antibody - Cat. #: CSB-PA096056","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Anthracycline associated resistance ARX antibody; Anthracycline-associated resistance ARX antibody; ARX antibody; FLJ13058 antibody; HRIHFB2115 antibody; SAE 2 antibody; SAE2 antibody; SAE2_HUMAN antibody; SUMO 1 activating enzyme subunit 2 antibody; SUMO activating enzyme subunit 2 antibody; SUMO-activating enzyme subunit 2 antibody; UBA2 antibody; UBA2 ubiquitin activating enzyme E1 homolog antibody; Ubiquitin like 1 activating enzyme E1B antibody; Ubiquitin like modifier activating enzyme 2 antibody; Ubiquitin-like 1-activating enzyme E1B antibody; UBLE1B antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q9UBT2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from C-terminal of Human Uba2.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2\/SAE2.\u003cbr\u003e\u003cbr\u003eMark H. L. Lambermon, Mol. Cell. Biol., Jun 2002; 22: 4346 - 4357. \u003cbr\u003eKyoung-Seok Ryu, J. Biol. Chem., Sep 2003; 278: 36621 - 36627. \u003cbr\u003eR. Jrgen Dohmen, J. Biol. Chem., Jul 1995; 270: 18099. \u003cbr\u003eYoshiaki Azuma, FASEB J, Jun 2001; 10.1096.\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:UBA2\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cell biology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483973365860,"sku":"CSB-PA096056","price":731.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_64b47f33-903e-420b-8b3b-dfd5c1a4d600.jpg?v=1660085048","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/uba2-antibody-cat-csb-pa096056","provider":"GeneBio ","version":"1.0","type":"link"}