{"product_id":"rrm2b-antibody-cat-csb-pa745339esr1hu","title":"RRM2B Antibody - Cat. #: CSB-PA745339ESR1HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:DKFZp686M05248 antibody; MGC102856 antibody; MGC42116 antibody; MTDPS8A antibody; MTDPS8B antibody; p53 inducible ribonucleotide reductase small subunit 2 homolog antibody; p53 inducible ribonucleotide reductase small subunit 2 like protein antibody; P53 inducible ribonucleotide reductase small subunit 2 short form beta antibody; p53 R2 antibody; p53-inducible ribonucleotide reductase small subunit 2-like protein antibody; p53R2 antibody; Ribonucleoside diphosphate reductase M2 subunit B antibody; Ribonucleoside-diphosphate reductase subunit M2 B antibody; Ribonucleotide reductase M2 B (TP53 inducible) antibody; Ribonucleotide reductase M2 B antibody; Ribonucleotide reductase small subunit like 2 p53 inducible antibody; RIR2B_HUMAN antibody; RRM 2B antibody; RRM2B antibody; TP53 inducible ribonucleotide reductase M2 B antibody; TP53-inducible ribonucleotide reductase M2 B antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q7LG56\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Ribonucleoside-diphosphate reductase subunit M2 B protein (1-351AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC, IP; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Plays a pivotal role in cell survival by repairing damaged DNA in a p53\/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen Affinity Purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:RRM2B\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling; Cancer; Metabolism\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40486052823140,"sku":"CSB-PA745339ESR1HU","price":409.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_bf6af5d2-298b-4bb5-ae61-d2b278e5f964.jpg?v=1660140093","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/rrm2b-antibody-cat-csb-pa745339esr1hu","provider":"GeneBio ","version":"1.0","type":"link"}