{"product_id":"rnf19a-antibody-cat-csb-pa868327la01hu","title":"RNF19A Antibody - Cat. #: CSB-PA868327LA01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:AA032313 antibody; DKFZP566B1346 antibody; Dorfin antibody; Double ring finger protein antibody; Double ring-finger protein antibody; E3 ubiquitin-protein ligase RNF19A antibody; p38 antibody; p38 protein antibody; Ring finger protein 19 antibody; RING finger protein 19A antibody; Ring IBR ring domain containing protein Dorfin antibody; RN19A_HUMAN antibody; RNF19 antibody; RNF19A antibody; Ubce7ip2 antibody; UIP117 antibody; XYbp antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q9NV58\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human E3 ubiquitin-protein ligase RNF19A protein (741-825AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC; Recommended dilution: IHC:1:200-1:500\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as SNCAIP or CASR. Specifically ubiquitinates pathogenic SOD1 variants, which leads to their proteasomal degradation and to neuronal protection.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, pH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:RNF19A\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Neuroscience; Cell biology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40487202619492,"sku":"CSB-PA868327LA01HU","price":409.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_b253de80-a908-48fe-8186-a73850fc5924.jpg?v=1660160969","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/rnf19a-antibody-cat-csb-pa868327la01hu","provider":"GeneBio ","version":"1.0","type":"link"}