{"product_id":"rnf138-antibody-cat-csb-pa994526","title":"RNF138 Antibody - Cat. #: CSB-PA994526","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:E3 ubiquitin protein ligase RNF138 antibody; E3 ubiquitin-protein ligase RNF138 antibody; hNARF antibody; HSD 4 antibody; HSD4 antibody; MGC8758 antibody; NARF antibody; Nemo like kinase associated RING finger protein antibody; Nemo-like kinase-associated RING finger protein antibody; NLK associated RING finger protein antibody; NLK-associated RING finger protein antibody; RING finger protein 138 antibody; ring finger protein 138, E3 ubiquitin protein ligase antibody; RN138_HUMAN antibody; Rnf138 antibody; STRIN antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q8WVD3\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from internal of Human RNF138.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:3000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF\/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt\/beta-catenin-mediated signaling pathway.\u003cbr\u003e\u003cbr\u003eWang L., Submitted (APR-2000) to the EMBL\/GenBank\/DDBJ databases.\u003cbr\u003eOta T., Nat. Genet. 36:40-45(2004).\u003cbr\u003eKalnine N., Submitted (MAY-2003) to the EMBL\/GenBank\/DDBJ databases.\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:RNF138\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling;Cell biology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483743137892,"sku":"CSB-PA994526","price":720.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_2237c9fe-ff60-4302-bbcb-cc140a3613e2.jpg?v=1660075096","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/rnf138-antibody-cat-csb-pa994526","provider":"GeneBio ","version":"1.0","type":"link"}