{"product_id":"recombinant-sdhb-monoclonal-antibody","title":"Recombinant SDHB Monoclonal Antibody","description":"\u003cp\u003e\u003cb\u003eSize:\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e:Store at -20℃ Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eShipping\u003c\/b\u003e:Ice bag\u003c\/p\u003e\u003cp\u003e\u003cb\u003eExp date\u003c\/b\u003e:12 months\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCategory ID_II\u003c\/b\u003e:Primary Antibodies\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCategory ID_III\u003c\/b\u003e:Recombinant Antibodies;Monoclonal Antibodies\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAbbreviation\u003c\/b\u003e:SDHB\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Synonym\u003c\/b\u003e:PGL;CWS;SDHB;CWS2;IP;PGL4;SDH;SDH1;SDH2;SDHIP;PGL4;SDH;SDH1;SDH2;SdhB;SDHIP;DHSB;FLJ92337;homolog of;iron sulfur (Ip);Iron sulfur subunit;Iron sulfur subunit of complex II;Iron-sulfur subunit of complex II;mitochondrial;PGL 4;S. cerevisiae;SDH 1;subunit B;Succinate dehydrogenase [ubiquinone] iron sulfur protein mitochondrial;Succinate dehydrogenase [ubiquinone] iron sulfur subunit;Succinate dehydrogenase [ubiquinone] iron-sulfur subunit;Succinate Dehydrogenase 1 Iron Sulfur Subunit;Succinate Dehydrogenase 2;succinate dehydrogenase complex;Succinate dehydrogenase complex iron sulfur subunit B;Succinate dehydrogenase complex subunit B iron sulfur;Succinate Dehydrogenase Complex Subunit B Iron Sulfur Protein;Succinate dehydrogenase iron sulfur protein\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Signal Transduction;Cell Biology;Cancer;Metabolism\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugation\u003c\/b\u003e:Unconjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies reactivity\u003c\/b\u003e:Human;Mouse;Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e:WB\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG,κ\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Monoclonal;Recombinant\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone NO.\u003c\/b\u003e:4F12\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUNIProt ID\u003c\/b\u003e:P21912\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAccession\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConcentration\u003c\/b\u003e:0.2 mg\/mL\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human SDHB protein\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification method\u003c\/b\u003e:Protein A\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDilution\u003c\/b\u003e:WB 1:2000-1:10000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCalculated MW\u003c\/b\u003e:31 kDa\u003c\/p\u003e\u003cp\u003e\u003cb\u003eObservedMW\u003c\/b\u003e:31 kDa\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48644767154276,"sku":"AN301365L","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_a4a0fe88-b897-4261-a49a-fb66f7400c14.jpg?v=1782653630","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/recombinant-sdhb-monoclonal-antibody","provider":"GeneBio ","version":"1.0","type":"link"}