{"product_id":"recombinant-mouse-bloom-syndrome-protein-homologblm-partial","title":"Recombinant Mouse Bloom syndrome protein homolog(Blm) ,partial","description":"\u003cp\u003e\u003cb\u003e\u0026gt;Several Other Sizes Are Also Available. Please Inquire.  Default Size\u003c\/b\u003e: 200ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUpdated Date\u003c\/b\u003e: Stock Protein updated on 20170725\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch areas\u003c\/b\u003e: Neuroscience \u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget \/ Protein\u003c\/b\u003e: Blm\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBiologically active\u003c\/b\u003e: Not Tested\u003c\/p\u003e\u003cp\u003e\u003cb\u003eExpression system\u003c\/b\u003e: E.coli\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies of origin\u003c\/b\u003e: Mus musculus (Mouse)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDelivery time\u003c\/b\u003e: 3-7 business days\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniprot ID\u003c\/b\u003e: O88700\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAA Sequence\u003c\/b\u003e: INAALLGEDCFILMPTGGGKSLCYQLPACVSPGVTIVISPLRSLIVDQVQKLTSFDIPATYLTGDKTDSEAANIYLQLSKKDPIIKLLYVTPEKVCASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRPQ\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTag info\u003c\/b\u003e: N-terminal 10xHis-tagged and C-terminal MYC-tagged\u003c\/p\u003e\u003cp\u003e\u003cb\u003eExpression Region\u003c\/b\u003e: 684-859aa\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProtein length\u003c\/b\u003e: Partial\u003c\/p\u003e\u003cp\u003e\u003cb\u003eMW\u003c\/b\u003e: 24.7 kDa\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAlternative Name(s)\u003c\/b\u003e: RecQ helicase homolog\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRelevance\u003c\/b\u003e: Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReference\u003c\/b\u003e: \"Point mutations causing Bloom's syndrome abolish ATPase and DNA helicase activities of the BLM protein.\"\nBahr A., de Graeve F., Kedinger C., Chatton B.\nOncogene 17:2565-2571(1998) \u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e: Greater than 90% as determined by SDS-PAGE.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. \nGenerally, the shelf life of liquid form is 6 months at -20℃\/-80℃. The shelf life of lyophilized form is 12 months at -20℃\/-80℃.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eNotes\u003c\/b\u003e: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":39766651371620,"sku":"CSB-EP002715MO","price":1057.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_f5e2c6eb-d458-493d-872e-4d43bcc8dd19.jpg?v=1659192040","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/recombinant-mouse-bloom-syndrome-protein-homologblm-partial","provider":"GeneBio ","version":"1.0","type":"link"}