{"product_id":"recombinant-human-metalloendopeptidase-oma1-mitochondrialoma1-active","title":"Recombinant Human Metalloendopeptidase OMA1, mitochondrial(OMA1) (Active)","description":"\u003cp\u003e\u003cb\u003e\u0026gt;Several Other Sizes Are Also Available. Please Inquire.  Default Size\u003c\/b\u003e: 10ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUpdated Date\u003c\/b\u003e: Stock Protein updated on 20170725\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch areas\u003c\/b\u003e: Cell Biology\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget \/ Protein\u003c\/b\u003e: OMA1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBiologically active\u003c\/b\u003e: Active\u003c\/p\u003e\u003cp\u003e\u003cb\u003eExpression system\u003c\/b\u003e: in vitro E.coli expression system\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies of origin\u003c\/b\u003e: Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDelivery time\u003c\/b\u003e: 3-7 business days\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniprot ID\u003c\/b\u003e: Q96E52\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAA Sequence\u003c\/b\u003e: HVFFRFNSLSNWRKCNTLASTSRGCHQVQVNHIVNKYQGLGVNQCDRWSFLPGNFHFYSTFNNKRTGGLSSTKSKEIWRITSKCTVWNDAFSRQLLIKEVTAVPSLSVLHPLSPASIRAIRNFHTSPRFQAAPVPLLLMILKPVQKLFAIIVGRGIRKWWQALPPNKKEVVKENIRKNKWKLFLGLSSFGLLFVVFYFTHLEVSPITGRSKLLLLGKEQFRLLSELEYEAWMEEFKNDMLTEKDARYLAVKEVLCHLIECNKDVPGISQINWVIHVVDSPIINAFVLPNGQMFVFTGFLNSVTDIHQLSFLLGHEIAHAVLGHAAEKAGMVHLLDFLGMIFLTMIWAICPRDSLALLCQWIQSKLQEYMFNRPYSRKLEAEADKIGLLLAAKACADIRASSVFWQQMEFVDSLHGQPKMPEWLSTHPSHGNRVEYLDRLIPQALKIREMCNCPPLSNPDPRLLFKLSTKHFLEESEKEDLNITKKQKMDTLPIQKQEQIPLTYIVEKRTGS\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTag info\u003c\/b\u003e: N-terminal 6xHis-SUMO-tagged\u003c\/p\u003e\u003cp\u003e\u003cb\u003eExpression Region\u003c\/b\u003e: 14-524aa\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProtein length\u003c\/b\u003e: Full Length of Mature Protein\u003c\/p\u003e\u003cp\u003e\u003cb\u003eMW\u003c\/b\u003e: 74.7 kDa\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAlternative Name(s)\u003c\/b\u003e: Metalloprotease-related protein 1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRelevance\u003c\/b\u003e: Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReference\u003c\/b\u003e: \"Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells.\"\nHead B., Griparic L., Amiri M., Gandre-Babbe S., van der Bliek A.M.\nJ. Cell Biol. 187:959-966(2009)\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e: Greater than 90% as determined by SDS-PAGE.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. \nGenerally, the shelf life of liquid form is 6 months at -20℃\/-80℃. The shelf life of lyophilized form is 12 months at -20℃\/-80℃.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eNotes\u003c\/b\u003e: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":39766659727460,"sku":"CSB-CF856923HU","price":1621.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_b75871d2-173d-4614-9b1a-688611efb61d.jpg?v=1659191983","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/recombinant-human-metalloendopeptidase-oma1-mitochondrialoma1-active","provider":"GeneBio ","version":"1.0","type":"link"}