{"product_id":"recombinant-cd40-monoclonal-antibody","title":"Recombinant CD40 Monoclonal Antibody","description":"\u003cp\u003e\u003cb\u003eSize:\u003c\/b\u003e:50μL\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e:Store at -20℃ Valid for 12 months. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eShipping\u003c\/b\u003e:Ice bag\u003c\/p\u003e\u003cp\u003e\u003cb\u003eExp date\u003c\/b\u003e:12 months\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCategory ID_II\u003c\/b\u003e:Primary Antibodies\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCategory ID_III\u003c\/b\u003e:Monoclonal Antibodies;Recombinant Antibodies\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAbbreviation\u003c\/b\u003e:CD40\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Synonym\u003c\/b\u003e:CDW;B-cell surface antigen CD;Tumor necrosis factor receptor superfamily member;TNFRSF;CD40;Bp50;CDW40;TNFRSF5;p50;Tumor necrosis factor receptor superfamily member 5;B-cell surface antigen CD40;CD40L receptor;TNFRSF5;AI326936;B cell associated molecule CD40;B cell surface antigen CD40;B cell-associated molecule;CD 40;CD40 (protein);CD40 antigen;CD40 antigen (TNF receptor superfamily member 5);CD40 molecule;CD40 protein;CD40 type II isoform;GP39;HIGM1;IGM;IMD3;isoform CRA_a;member 5;MGC9013;Nerve growth factor receptor related B lymphocyte activation molecule;OTTHUMP00000031699;OTTHUMP00000031700;TBAM;T-BAM;TNF receptor superfamily member 5;TNR5;TRAP;Tumor necrosis factor receptor superfamily;Tumor necrosis factor receptor superfamily member 5 precursor\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Immunology;Cardiovascular;Stem Cells\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugation\u003c\/b\u003e:Unconjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies reactivity\u003c\/b\u003e:Human;\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e:WB;IHC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG,κ\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Monoclonal;Recombinant\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone NO.\u003c\/b\u003e:A417\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUNIProt ID\u003c\/b\u003e:P25942\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAccession\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:The CD40 antigen is a 44-48 kDa type I integral membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. This antigen is found on B cell lines, is strongly expressed by interdigitating cells (IDC), basal epithelial cells, and is also present on macrophages, some endothelial cells, and follicular dendritic cells. It is a well-known regulator of T cell immunity including in cancer. CD40-ligand, primarily expressed on activated T cells, interacts with CD40 on APCs resulting in a ‘licensed’ state.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConcentration\u003c\/b\u003e:1 mg\/mL\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant human CD40 fragment\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification method\u003c\/b\u003e:Protein A purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDilution\u003c\/b\u003e:WB 1:1000-1:5000;IHC 1:200-1:1000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eCalculated MW\u003c\/b\u003e:32 kDa\u003c\/p\u003e\u003cp\u003e\u003cb\u003eObservedMW\u003c\/b\u003e:44-48 kDa\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48644779802724,"sku":"AN301709L","price":424.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_6a515282-c393-41d2-8c24-c5215593e37b.jpg?v=1782654121","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/recombinant-cd40-monoclonal-antibody","provider":"GeneBio ","version":"1.0","type":"link"}