{"product_id":"rad18-antibody-cat-csb-pa274794","title":"RAD18 Antibody - Cat. #: CSB-PA274794","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:2810024C04Rik antibody; DNA repair protein rad18 antibody; E3 ubiquitin-protein ligase RAD18 antibody; EC 6.3.2.- antibody; hHR 18 antibody; hHR18 antibody; hRAD 18 antibody; hRAD18 antibody; MGC156682 antibody; Postreplication repair E3 ubiquitin-protein ligase RAD18 antibody; Postreplication repair protein hRAD18p antibody; Postreplication repair protein RAD18 antibody; RAD 18 antibody; RAD18 antibody; RAD18 homolog (S. cerevisiae) antibody; RAD18 homolog antibody; RAD18 S. cerevisiae homolog antibody; RAD18 S. cerevisiae homolog of antibody; RAD18 transcript variant antibody; RAD18_HUMAN antibody; Rad18sc antibody; Radiation sensitivity protein 18 antibody; RING finger protein 73 antibody; RNF 73 antibody; RNF73 antibody; Structural maintenance of chromosomes protein 6 antibody; YCR066W antibody; YCR66W antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q9NS91\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from internal of Human RAD18.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:3000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity.\u003cbr\u003e\u003cbr\u003eTateishi S., Proc. Natl. Acad. Sci. U.S.A. 97:7927-7932(2000).\u003cbr\u003eXin H., Nucleic Acids Res. 28:2847-2854(2000).\u003cbr\u003eMuzny D.M., Nature 440:1194-1198(2006).\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:RAD18\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling;Cell biology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483743072356,"sku":"CSB-PA274794","price":718.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_3d738d28-d7ef-4945-890e-08f53dee722e.jpg?v=1660075095","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/rad18-antibody-cat-csb-pa274794","provider":"GeneBio ","version":"1.0","type":"link"}