{"product_id":"ppp1r14a-ab-38-antibody-cat-csb-pa794704","title":"PPP1R14A (Ab-38) Antibody - Cat. #: CSB-PA794704","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:17 kDa PKC-potentiated inhibitory protein of PP1 antibody; 17-KDa protein antibody; 17kDa PKC potentiated inhibitory protein of PP1 antibody; CPI 17 alpha antibody; CPI 17 antibody; CPI 17alpha antibody; CPI-17 antibody; CPI17 alpha antibody; CPI17 antibody; PKC potentiated inhibitory protein of PP1 antibody; PKC potentiated inhibitory protein of PP1, 17-KD antibody; PP14A_HUMAN antibody; PPP1INL antibody; Ppp1r14a antibody; Protein kinase C-potentiated inhibitor of protein phosphatase 1, 17-KD antibody; Protein kinase C-potentiated inhibitor protein of 17 kDa antibody; Protein phosphatase 1 antibody; Protein phosphatase 1 regulatory (inhibitor) subunit 14A antibody; Protein phosphatase 1 regulatory subunit 14A antibody; Regulatory subunit 14A  antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q96A00\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around aa.36~40 (R-V-T-V-K) derived from Human CPI17a.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IF; IF:1:100-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.\u003cbr\u003e\u003cbr\u003eHagerty L, et al. (2007) J Biol Chem. 2007; 282(7):4884-93\u003cbr\u003eSeok YM, et al. (2008) J Pharmacol Exp Ther. \u003cbr\u003eNiiro N et al. (2003) Biochem J. 2003 ;369(Pt 1):117-28\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Supplied at 1.0mg\/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:PPP1R14A\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483683663972,"sku":"CSB-PA794704","price":730.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_99402cd7-ae6e-4b0c-bc27-75fbc75f2aba.jpg?v=1660073796","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/ppp1r14a-ab-38-antibody-cat-csb-pa794704","provider":"GeneBio ","version":"1.0","type":"link"}