{"product_id":"phospho-ncf1-ser345-antibody-cat-csb-pa048500","title":"Phospho-NCF1 (Ser345) Antibody - Cat. #: CSB-PA048500","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:47 kDa autosomal chronic granulomatous disease protein antibody; 47 kDa neutrophil oxidase factor antibody; NADPH oxidase organizer 2 antibody; NCF 47K antibody; NCF-1 antibody; NCF-47K antibody; Ncf1 antibody; NCF1_HUMAN antibody; Neutrophil cytosol factor 1 antibody; Neutrophil cytosolic factor 1 antibody; neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) antibody; Neutrophil NADPH oxidase factor 1 antibody; Nox organizer 2 antibody; Nox organizing protein 2 antibody; Nox-organizing protein 2 antibody; NOXO2 antibody; p47 phox antibody; p47-phox antibody; SH3 and PX domain containing protein 1A antibody; SH3 and PX domain-containing protein 1A antibody; SH3PXD1A antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P14598\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around phosphorylation site of Serine 345(P-Q-S(p)-P-G) derived from Human Nuclear p47 phox.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC; WB:1:500-1:1000, IHC:1:50-1:100\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003eNCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).\u003cbr\u003e\u003cbr\u003eVolpp B.D., Proc. Natl. Acad. Sci. U.S.A. 86:7195-7199(1989).\u003cbr\u003eLomax K.J., Science 245:409-412(1989).\u003cbr\u003eRodaway A.R.F., Mol. Cell. Biol. 10:5388-5396(1990).\u003cbr\u003e \u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:NCF1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer;Metabolism;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40484047159396,"sku":"CSB-PA048500","price":876.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_454154cf-7a82-46ed-8849-063e0706ac58.jpg?v=1660086912","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/phospho-ncf1-ser345-antibody-cat-csb-pa048500","provider":"GeneBio ","version":"1.0","type":"link"}