{"product_id":"phospho-fcgr2b-tyr292-antibody-cat-csb-pa785845","title":"Phospho-FCGR2B (Tyr292) Antibody - Cat. #: CSB-PA785845","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:CD32 antibody; CD32 antigen  antibody; CD32B antibody; CDw32 antibody; Fc fragment of IgG; low affinity II; receptor for (CD32) antibody; Fc fragment of IgG; low affinity IIb; receptor  antibody; Fc fragment of IgG; low affinity IIb; receptor (CD32) antibody; Fc fragment of IgG; low affinity IIb; receptor for (CD32) antibody; Fc fragment of IgG; low affinity IIb; receptor for antibody; Fc gamma receptor IIB antibody; Fc gamma RII antibody; Fc gamma RIIB antibody; Fc-gamma RII antibody; Fc-gamma RII-b antibody; Fc-gamma-RIIb antibody; FCG2 antibody; FCG2B_HUMAN antibody; Fcgr2 antibody; FCGR2B antibody; FCRII antibody; FcRII-b antibody; IGFR2 antibody; IgG Fc receptor II beta antibody; IgG Fc receptor II-b antibody; Low affinity immunoglobulin gamma Fc region receptor II antibody; Low affinity immunoglobulin gamma Fc region receptor II-b antibody; Ly-17 antibody; Lym 1 antibody; Lymphocyte antigen 17 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P31994\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y(p)-S-L) derived from Human CD32.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:1000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003eReceptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.\u003cbr\u003e\u003cbr\u003eStuart S.G., EMBO J. 8:3657-3666(1989).\u003cbr\u003eBrooks D.G., J. Exp. Med. 170:1369-1385(1989).\u003cbr\u003eEngelhardt W., Eur. J. Immunol. 20:1367-1377(1990).\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:FCGR2B\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Immunology;Stem cells\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40484028907620,"sku":"CSB-PA785845","price":885.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_aaf0ee12-c9a0-4597-ae65-b10a7562e082.jpg?v=1660086423","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/phospho-fcgr2b-tyr292-antibody-cat-csb-pa785845","provider":"GeneBio ","version":"1.0","type":"link"}