{"product_id":"oma1-antibody-cat-csb-pa856923la01hu","title":"OMA1 Antibody - Cat. #: CSB-PA856923LA01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:2010001O09Rik antibody; DAB1 antibody; FLJ33782 antibody; Metalloendopeptidase OMA1 antibody; Metalloendopeptidase OMA1; mitochondrial antibody; Metalloprotease-related protein 1 antibody; mitochondrial antibody; MPRP 1 antibody; MPRP-1 antibody; MPRP1 antibody; OMA1 antibody; OMA1 homolog zinc metallopeptidase antibody; OMA1 homolog; zinc metallopeptidase (S. cerevisiae) antibody; OMA1 zinc metallopeptidase antibody; OMA1 zinc metallopeptidase homolog antibody; OMA1_HUMAN antibody; Overlapping activity with M-AAA protease antibody; Overlapping with the m-AAA protease 1 homolog antibody; peptidase antibody; YKR087C antibody; Zinc metallopeptidase OMA1 antibody; ZMPOMA1 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q96E52\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Metalloendopeptidase OMA1, mitochondrial protein (22-194AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, PH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:OMA1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cell biology; Metabolism\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40485750440036,"sku":"CSB-PA856923LA01HU","price":409.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_fa69a6fd-20ab-43f7-bf89-4b0298daa01e.jpg?v=1660135005","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/oma1-antibody-cat-csb-pa856923la01hu","provider":"GeneBio ","version":"1.0","type":"link"}