{"product_id":"nr4a1-ab-351-antibody-cat-csb-pa568320","title":"NR4A1 (Ab-351) Antibody - Cat. #: CSB-PA568320","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Early response protein NAK1 antibody; GFRP 1 antibody; GFRP antibody; GFRP1 antibody; Growth factor inducible nuclear protein N10 antibody; Growth Factor Inducible Nuclear Protein NP10 antibody; Growth Factor Response Protein 1 antibody; Hbr1 antibody; HMR antibody; Hormone Receptor antibody; MGC9485 antibody; N10 antibody; N10 nuclear protein antibody; NAK 1 antibody; NAK1 antibody; Nerve growth factor IB nuclear receptor variant 1 antibody; NGFIB antibody; NP 10 antibody; NP10 antibody; NR4A1 antibody; NR4A1_HUMAN antibody; Nuclear hormone receptor NUR\/77 antibody; Nuclear Hormone Receptor TR3 antibody; Nuclear receptor subfamily 4 group A member 1 antibody; NUR77 antibody; NUR77; mouse; homolog of antibody; Orphan nuclear receptor HMR antibody; Orphan nuclear receptor NR4A1 antibody; Orphan nuclear receptor TR3 antibody; Orphan receptor tr3 antibody; Receptor NGFIB antibody; ST 59 antibody; ST-59 antibody; ST59 antibody; Steroid receptor TR3 antibody; Testicular receptor 3 antibody; TR 3 antibody; TR3 antibody; TR3 orphan receptor antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P22736\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized non-phosphopeptide derived from Human Nuclear Receptor NR4A1 around the phosphorylation site of serine 351 (L-P-S(p)-K-P).\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' By similarity. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.\u003cbr\u003e\u003cbr\u003eNakai A., Mol. Endocrinol. 4:1438-1443(1990).\u003cbr\u003eChang C., J. Steroid Biochem. 34:391-395(1989).\u003cbr\u003eThe MGC Project Team; Genome Res. 14:2121-2127(2004).\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:NR4A1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling;Cancer;Cell biology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483997876324,"sku":"CSB-PA568320","price":731.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_a27a2c0d-6399-404f-9ded-9c9ec99adb17.jpg?v=1660085749","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/nr4a1-ab-351-antibody-cat-csb-pa568320","provider":"GeneBio ","version":"1.0","type":"link"}