{"product_id":"lilrb1-antibody-cat-csb-pa847747la01hu","title":"LILRB1 Antibody - Cat. #: CSB-PA847747LA01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:CD85 antibody; CD85 antigen antibody; CD85 antigen like family member J antibody; CD85 antigen-like family member J antibody; CD85j antibody; CD85j antigen antibody; Ig like transcript 2 antibody; ILT 2 antibody; ILT-2 antibody; ILT2 antibody; immunoglobulin like transcript 2 antibody; Immunoglobulin-like transcript 2 antibody; leukocyte Ig like receptor 1 antibody; Leukocyte immunoglobulin like receptor 1 antibody; leukocyte immunoglobulin like receptor subfamily B member 1 antibody; Leukocyte immunoglobulin like receptor subfamily B member 1 precursor antibody; leukocyte immunoglobulin like receptor subfamily B member 1 soluble isoform antibody; leukocyte immunoglobulin like receptor, subfamily B, member 1 antibody; Leukocyte immunoglobulin-like receptor 1 antibody; Leukocyte immunoglobulin-like receptor subfamily B member 1 antibody; leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform antibody; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 antibody; LILRB1 antibody; LIR 1 antibody; LIR-1 antibody; LIR1 antibody; LIRB1_HUMAN antibody; MIR 7 antibody; MIR-7 antibody; MIR7 antibody; Monocyte\/macrophage immunoglobulin like receptor 7 antibody; Monocyte\/macrophage immunoglobulin-like receptor 7 antibody; PIR B antibody; PIRB antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q8NHL6\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Leukocyte immunoglobulin-like receptor subfamily B member 1 protein (483-650AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Receptor for H301\/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Preservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, pH 7.4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:LILRB1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Immunology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40487412858980,"sku":"CSB-PA847747LA01HU","price":409.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_f2089ec8-d05e-4554-a7e5-8806c5509824.jpg?v=1660164870","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/lilrb1-antibody-cat-csb-pa847747la01hu","provider":"GeneBio ","version":"1.0","type":"link"}