{"product_id":"klf10-antibody-cat-csb-pa621651dsr2hu","title":"KLF10 Antibody - Cat. #: CSB-PA621651DSR2HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:Early growth response; alpha antibody; Early growth response; alpha like antibody; EGR A antibody; EGR alpha  antibody; EGR(A) antibody; EGR-alpha antibody; EGRA antibody; Egral antibody; EGRalpha antibody; Gdnfif antibody; KLF 10 antibody; KLF10 antibody; KLF10_HUMAN antibody; Krueppel like factor 10 antibody; Krueppel like factor10 antibody; Krueppel-like factor 10 antibody; Kruppel like factor 10 antibody; mGIF antibody; TGF-beta- inducible early gene antibody; TGFB inducible early growth response 1 antibody; TGFB inducible early growth response antibody; TGFB inducible early growth response protein 1 antibody; TGFB-inducible early growth response protein 1 antibody; TIEG 1 antibody; TIEG antibody; TIEG-1 antibody; TIEG1 antibody; Transforming growth factor beta inducible early growth response antibody; Transforming growth factor beta inducible early growth response protein 1 antibody; Transforming growth factor-beta-inducible early growth response protein 1 antibody; Zinc finger transcription factor TIEG antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:Q13118\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Krueppel-like factor 10 protein (1-250AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Transcriptional repressor which binds to the consensus sequence 5\\\\\\'-GGTGTG-3\\\\\\'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL\/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity). May play a role in the cell cycle regulation.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen Affinity Purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:KLF10\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Epigenetics and Nuclear Signaling; Cancer; Cardiovascular; Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40486045679716,"sku":"CSB-PA621651DSR2HU","price":409.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_1fa27ffd-363a-4d5d-aad9-30fc4fba3800.jpg?v=1660139986","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/klf10-antibody-cat-csb-pa621651dsr2hu","provider":"GeneBio ","version":"1.0","type":"link"}