{"product_id":"invivomab-anti-human-ifng-ifn-gamma-iv0049","title":"InVivoMAb Anti-Human IFNG\/IFN-gamma (Iv0049)","description":"\u003cp\u003e\u003cb\u003eSize\u003c\/b\u003e:100ug\u003c\/p\u003e\u003cp\u003e\u003cb\u003eDescription\u003c\/b\u003e:Iv0049 is a humanized monoclonal antibody that targets and neutralizes interferon-gamma (IFN-γ), a cytokine associated with inflammatory pathways. It has been investigated for potential use in autoimmune diseases such as Crohn’s disease. By binding IFN-γ, Iv0049 reduces downstream inflammatory signaling and its detrimental effects on intestinal barrier integrity. Early clinical studies have reported signs of therapeutic activity and generally manageable tolerability, although some serious adverse events, including disease exacerbation, were observed. Iv0049 has not been described as a currently marketed therapy, and its broader clinical development status remains unclear.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost species\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage buffer\u003c\/b\u003e:0.01M PBS, pH 7.4.\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurity\u003c\/b\u003e:\u0026gt;95% as determined by SDS-PAGE.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications\u003c\/b\u003e:ELISA, Neutralization, FCM\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget\u003c\/b\u003e:Interferon gamma, IFN-gamma, Immune interferon, IFNG, IFN-γ\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification\u003c\/b\u003e:Protein A\/G purified from cell culture supernatant.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eEndotoxin level\u003c\/b\u003e:Please contact us for this information.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAccession\u003c\/b\u003e:P01579\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStability and Storage\u003c\/b\u003e:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone ID\u003c\/b\u003e:Iv0049\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Usage Information\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePredicted molecular weight\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eNote\u003c\/b\u003e:For research use only. Not suitable for clinical or therapeutic use.\u003c\/p\u003e","brand":"GeneBio Systems","offers":[{"title":"Default Title","offer_id":48672584859748,"sku":"HF813010","price":642.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/no_image_default_image-jpeg_4066f0ce-4f23-4aa9-83a5-64ac21088885.jpg?v=1782932005","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/invivomab-anti-human-ifng-ifn-gamma-iv0049","provider":"GeneBio ","version":"1.0","type":"link"}