{"product_id":"ifna1-antibody-cat-csb-pa365592ka01hu","title":"IFNA1 Antibody - Cat. #: CSB-PA365592KA01HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:IFL antibody; IFN alpha antibody; IFN alpha 1\/13 antibody; IFN alpha 1b antibody; IFN alphaD antibody; IFN antibody; IFN-alpha-1\/13 antibody; IFNA@ antibody; IFNA1 antibody; IFNA1_HUMAN antibody; IFNA13 antibody; Interferon alpha 1 antibody; Interferon alpha-1\/13 antibody; Interferon alpha-D antibody; Interferon alpha1 antibody; Interferon, alpha 13 antibody; LeIF D antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P01562\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant protein of Human IFN-? \u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:2000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Interferon-?1 is a member of the Type I IFN family best known for their antiviral activity. Most nucleated cells produce one or more Type I IFNs in response to viral infection. Secreted Type I IFN then induces viral protective responses in neighboring non-infected cells. Type I IFNs also enhance virus-induced apoptosis. Other IFN-?1 activities include enhancement of dendritic cell maturation and cytotoxic T cell activity. IFN-?1 binds to the IFN-?R1 and IFN-?R2 heterodimer. Intracellular signaling through the Jak\/Stat pathway is best characterized. However, the PI3K, ERK, and p38 kinase pathways are also involved. The antiviral activities of the IFNs have led to their use in treating viral infections. Type I IFNs also appear to have an integral role in several autoimmune diseases.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Affinity purification\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Store at -20°C or -80°C. Avoid freeze \/ thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:IFNA1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer;Immunology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483673473124,"sku":"CSB-PA365592KA01HU","price":979.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_9f35137a-707a-40ec-9784-7671361f2d29.jpg?v=1660073544","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/ifna1-antibody-cat-csb-pa365592ka01hu","provider":"GeneBio ","version":"1.0","type":"link"}