{"product_id":"gzma-antibody-cat-csb-pa010081esr2hu","title":"GZMA Antibody - Cat. #: CSB-PA010081ESR2HU","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:50ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:CTL tryptase antibody; CTLA3 antibody; Cytolytic t cell and natural killer cell specific trypsin like serine protease antibody; Cytotoxic T lymphocyte associated serine esterase 3 antibody; Cytotoxic T lymphocyte proteinase 1 antibody; Cytotoxic T-lymphocyte proteinase 1 antibody; Fragmentin 1 antibody; Fragmentin-1 antibody; GRAA_HUMAN antibody; Granzyme 1 cytotoxic T lymphocyte associated serine esterase 3 antibody; Granzyme A (Cytotoxic T lymphocyte associated serine esterase 3, Hanukah factor serine protease) antibody; Granzyme A (granzyme 1, cytotoxic T lymphocyte associated serine esterase 3) antibody; Granzyme A antibody; Granzyme A precursor antibody; Granzyme-1 antibody; GZMA antibody; H factor antibody; Hanukah factor serine protease antibody; Hanukkah factor antibody; HF antibody; HFSP antibody; TSP1 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P12544\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Recombinant Human Granzyme A protein (29-262AA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, IHC; Recommended dilution: IHC:1:20-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after \\\\\\'Lys-31\\\\\\' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after \\\\\\'Lys-189\\\\\\', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antigen Affinity Purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:Liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:GZMA\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cell biology; Immunology\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40486017433700,"sku":"CSB-PA010081ESR2HU","price":409.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_b6059a24-9e66-4ae5-8ff6-494bcc47f9b2.jpg?v=1660139606","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/gzma-antibody-cat-csb-pa010081esr2hu","provider":"GeneBio ","version":"1.0","type":"link"}