{"product_id":"cnga1-antibody-cat-csb-pa265137","title":"CNGA1 Antibody - Cat. #: CSB-PA265137","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:cGMP gated cation channel alpha 1 antibody; cGMP-gated cation channel alpha-1 antibody; CNCG antibody; CNCG1 antibody; CNG 1 antibody; CNG channel alpha 1 antibody; CNG channel alpha-1 antibody; CNG-1 antibody; CNG1 antibody; Cnga1 antibody; CNGA1_HUMAN antibody; Cyclic nucleotide gated cation channel 1 antibody; Cyclic nucleotide gated channel alpha 1 antibody; Cyclic nucleotide gated channel photoreceptor antibody; Cyclic nucleotide-gated cation channel 1 antibody; Cyclic nucleotide-gated channel alpha-1 antibody; Cyclic nucleotide-gated channel antibody; Interleukin 1 homologue antibody; OTTHUMP00000218675 antibody; OTTHUMP00000223313 antibody; OTTHUMP00000223314 antibody; photoreceptor antibody; RCNC1 antibody; RCNCa antibody; RCNCalpha antibody; Rod photoreceptor cGMP gated channel subunit alpha antibody; Rod photoreceptor cGMP-gated channel subunit alpha antibody; RP49 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P29973\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Synthesized peptide derived from internal of Human CNGA1.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB; WB:1:500-1:3000\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors.\u003cbr\u003e\u003cbr\u003ePittler S.J., J. Biol. Chem. 267:6257-6262(1992).\u003cbr\u003eDhallan R.S., J. Neurosci. 12:3248-3256(1992).\u003cbr\u003eOta T., Nat. Genet. 36:40-45(2004).\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:CNGA1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Neuroscience;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483737108580,"sku":"CSB-PA265137","price":727.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_b21ff708-e70b-4ac3-9570-f5627c534fa0.jpg?v=1660075023","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/cnga1-antibody-cat-csb-pa265137","provider":"GeneBio ","version":"1.0","type":"link"}