{"product_id":"bcr-ab-177-antibody-cat-csb-pa929167","title":"BCR (Ab-177) Antibody - Cat. #: CSB-PA929167","description":"\u003cp\u003e\u003cb\u003eSize \u003c\/b\u003e:100ul\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone Number\u003c\/b\u003e:\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAliases\u003c\/b\u003e:ALL antibody; bcr antibody; BCR\/ABL FUSION GENE, INCLUDED antibody; BCR\/FGFR1 chimera protein antibody; BCR\/FGFR1 FUSION GENE, INCLUDED antibody; BCR\/PDGFRA FUSION GENE, INCLUDED antibody; BCR_HUMAN antibody; BCR1 antibody; Breakpoint cluster region antibody; Breakpoint cluster region protein antibody; CML antibody; D22S11 antibody; D22S662 antibody; FGFR1\/BCR chimera protein antibody; PHL antibody; Renal carcinoma antigen NY-REN-26 antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eProduct Type\u003c\/b\u003e:Polyclonal Antibody\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen Species\u003c\/b\u003e:Homo sapiens (Human)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eUniProt ID\u003c\/b\u003e:P11274\u003c\/p\u003e\u003cp\u003e\u003cb\u003eImmunogen\u003c\/b\u003e:Peptide sequence around aa. 175~179 (P-F-Y-V-N) derived from Human Bcr.\n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRaised in\u003c\/b\u003e:Rabbit\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecies Reactivity\u003c\/b\u003e:Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Applications\u003c\/b\u003e:ELISA, WB, IF; WB:1:500-1:1000, IF:1:100-1:200\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e:GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine\/threonine kinase activity.\u003cbr\u003e\u003cbr\u003eSattler M, et al. Mol Cell Biol. 1999 Nov; 19(11): 7473-7480.\u003cbr\u003eLi S et al. EMBO J. 2001 Dec 3; 20(23): 6793-6804.\u003cbr\u003eMillion RP, et,al. Mol Cell Biol. 2004 Jun; 24(11): 4685-4695.\u003cbr\u003eMalcolm A. Meyn, et al. . Biol. Chem., Oct 2006; 281: 30907 \n\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClonality\u003c\/b\u003e:Polyclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e:IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003ePurification Method\u003c\/b\u003e:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eConjugate\u003c\/b\u003e:Non-conjugated\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBuffer\u003c\/b\u003e:Supplied at 1.0mg\/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eForm\u003c\/b\u003e:liquid\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStroage\u003c\/b\u003e:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTarget Names\u003c\/b\u003e:BCR\u003c\/p\u003e\u003cp\u003e\u003cb\u003eResearch Areas\u003c\/b\u003e:Cancer;Signal transduction\u003c\/p\u003e","brand":"Gene Bio Systems","offers":[{"title":"Default Title","offer_id":40483781509220,"sku":"CSB-PA929167","price":731.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/products\/no_image_default_image-jpeg_e6409ded-1e85-4daa-80b9-847ada8512bb.jpg?v=1660076082","url":"https:\/\/www.genebiosystems.com\/en-us\/products\/bcr-ab-177-antibody-cat-csb-pa929167","provider":"GeneBio ","version":"1.0","type":"link"}