{"product_id":"transdetect-r-in-situ-click-tunel-imaging-kit-555-fluorophore","title":"TransDetect® In Situ Click TUNEL Imaging Kit-555 Fluorophore","description":"\u003cdiv class=\"page-title anchor\" data-anchor=\"introduce\"\u003e\n\u003ch3\u003eProduct Details\u003c\/h3\u003e\n\u003cdiv class=\"solid\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-brief\"\u003e\n\u003cp\u003e\u003cem\u003eTransDetect\u003c\/em\u003e\u003csup\u003e®\u003c\/sup\u003e In Situ Click TUNEL Imaging Kit-555 Fluorophore is a TUNEL assay reagent based on the Click reaction. In apoptosis, double-strand breaks or single strand breaks of genomic DNA can produce a large number of sticky 3'-OH ends. EdUTP is a dUTP nucleotide modified with a small alkyne moiety, which is more readily incorporated at the 3´-OH ends of fragmented DNA by the Terminal deoxynucleotidyl transferase (TdT) enzyme. A covalent reaction occurs between the azide and the alkyne moiety on EdUTP based on the Click reaction, and more sensitive TUNEL detection can be performed via fluorophore on the azide.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eat -20˚C in the dark for one year\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eShipping\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDry ice (-70℃)\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/div\u003e","brand":"Gene Bio Systems","offers":[{"title":"10 rxns","offer_id":46783129714788,"sku":"FA311-01","price":143200.0,"currency_code":"JPY","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0558\/8588\/9636\/files\/1_5fca2323-827a-4843-8173-0012740b8449.jpg?v=1756402774","url":"https:\/\/www.genebiosystems.com\/en-jp\/products\/transdetect-r-in-situ-click-tunel-imaging-kit-555-fluorophore","provider":"GeneBio ","version":"1.0","type":"link"}